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Sympathetic renal denervation: hypertension beyond SYMPLICITY. [Review]

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Citation: Cardiovascular Revascularization Medicine. 14(4):229-35, 2013 Jul-Aug.PMID: 23928314Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Hypertension/su [Surgery] | *Sympathectomy | Blood Pressure/ph [Physiology] | Brachytherapy/is [Instrumentation] | Brachytherapy/mt [Methods] | Humans | Hypertension/pp [Physiopathology] | Kidney/pp [Physiopathology] | Kidney/su [Surgery] | Renal Artery/ir [Innervation] | Renal Artery/pp [Physiopathology] | Renal Artery/su [Surgery] | Sympathectomy/is [Instrumentation] | Sympathectomy/mt [Methods]Year: 2013 Local holdings: Available in print through MWHC library: 2002 - presentISSN:

1878-0938

Name of journal: Cardiovascular revascularization medicine : including molecular interventionsAbstract: Despite a wide range of drug treatment for hypertension, resistant hypertension rates remain high. The Symplicity Renal Denervation System (Medtronic, Santa Rosa, CA), which creates renal nerve denervation, has shown initial success in lowering blood pressure among patients with resistant hypertension. Given the enormous market for this treatment approach, an estimated two dozen other companies are pursuing technologies with alternative approaches. Despite this fact, very little has been published on preclinical and clinical experience with these new devices. The current review summarizes the most prominent technologies in the pipeline and provides insight into the mechanism of action, preclinical, and clinical experience with these new devices. Copyright 2013. Published by Elsevier Inc.All authors: Barbash IM, Waksman RFiscal year: FY2014Digital Object Identifier:

http://dx.doi.org/10.1016/j.carrev.2013.02.004

Date added to catalog: 2014-08-21

Holdings ( 1 )
Title notes ( 3 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	23928314	Available		23928314

Available in print through MWHC library: 2002 - present

Despite a wide range of drug treatment for hypertension, resistant hypertension rates remain high. The Symplicity Renal Denervation System (Medtronic, Santa Rosa, CA), which creates renal nerve denervation, has shown initial success in lowering blood pressure among patients with resistant hypertension. Given the enormous market for this treatment approach, an estimated two dozen other companies are pursuing technologies with alternative approaches. Despite this fact, very little has been published on preclinical and clinical experience with these new devices. The current review summarizes the most prominent technologies in the pipeline and provides insight into the mechanism of action, preclinical, and clinical experience with these new devices. Copyright 2013. Published by Elsevier Inc.

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