Evaluation and Management of Congenital Bleeding Disorders. [Review]
Citation: Hematology - Oncology Clinics of North America. 31(6):1105-1122, 2017 DecPMID: 29078926Institution: MedStar Washington Hospital CenterDepartment: Emergency MedicineForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Blood Coagulation Disorders, Inherited/di [Diagnosis] | *Blood Coagulation Disorders, Inherited/dt [Drug Therapy] | *Blood Coagulation Factors/tu [Therapeutic Use] | *Emergency Medical Services/mt [Methods] | *Factor VIII/tu [Therapeutic Use] | *Fibrinogen/tu [Therapeutic Use] | Humans | Wounds and Injuries/di [Diagnosis] | Wounds and Injuries/th [Therapy]Year: 2017Local holdings: Available online from MWHC library: 1996 - presentISSN:- 0889-8588
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 29078926 | Available | 29078926 |
Available online from MWHC library: 1996 - present
Copyright (c) 2017 Elsevier Inc. All rights reserved.
Patients presenting to the emergency department with acute bleeding and a history of clotting or platelet disorder present a unique challenge to the emergency physician. The severity of bleeding presentation is based on mechanism as well as factor levels: patients with factor levels greater than 5% can respond to most minor hemostatic challenges, whereas those with factor levels less than 1% bleed with minor trauma or even spontaneously. Treatment should be initiated in consultation with the patient's hematologist using medications and specific factor replacement, except in rare, life-threatening, resource-poor situations, when cryoprecipitate or activated prothrombin complex may be considerations.
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