High-grade B-cell lymphoma masquerading as peritoneal lymphomatosis.

MedStar author(s):
Citation: BMJ Case Reports. 12(8), 2019 Aug 13.PMID: 31413062Institution: MedStar Washington Hospital CenterDepartment: Medicine/Internal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Lymphoma, Large B-Cell, Diffuse/di [Diagnosis] | Antineoplastic Combined Chemotherapy Protocols | Diabetes Mellitus, Type 2 | Diagnosis, Differential | Fatal Outcome | Humans | Hypertension | Lymphoma, Large B-Cell, Diffuse/dg [Diagnostic Imaging] | Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy] | Lymphoma, Large B-Cell, Diffuse/pa [Pathology] | Male | Middle Aged | Peritoneal Neoplasms/dg [Diagnostic Imaging] | Peritoneal Neoplasms/di [Diagnosis] | Peritoneal Neoplasms/dt [Drug Therapy] | Peritoneal Neoplasms/pa [Pathology] | Tomography, X-Ray ComputedYear: 2019ISSN:
  • 1757-790X
Name of journal: BMJ case reportsAbstract: Copyright (c) BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.Peritoneal lymphomatosis represents a rare presentation of any type of non-Hodgkin's lymphoma, with relatively few cases reported in the literature. We present here the case of a 61-year-old man who originally presented with increased abdominal distention associated with shortness of breath and diaphoresis who was found to have evidence of peritoneal carcinomatosis on CT scan. Biopsy confirmed diffuse large B-cell lymphoma, and the working diagnosis was subsequently modified to peritoneal lymphomatosis. The patient was treated with dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin and rituximab (DA-EPOCH-R) therapy with initially good response. His course was complicated by tumour lysis syndrome. We review the limited literature discussing peritoneal lymphomatosis and discuss the importance of facilitating rapid and efficacious treatment.All authors: Feigert J, Kareff S, Yin CFiscal year: FY2020Digital Object Identifier: ORCID: Date added to catalog: 2019-08-27
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Journal Article MedStar Authors Catalog Article 31413062 Available 31413062

Copyright (c) BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Peritoneal lymphomatosis represents a rare presentation of any type of non-Hodgkin's lymphoma, with relatively few cases reported in the literature. We present here the case of a 61-year-old man who originally presented with increased abdominal distention associated with shortness of breath and diaphoresis who was found to have evidence of peritoneal carcinomatosis on CT scan. Biopsy confirmed diffuse large B-cell lymphoma, and the working diagnosis was subsequently modified to peritoneal lymphomatosis. The patient was treated with dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin and rituximab (DA-EPOCH-R) therapy with initially good response. His course was complicated by tumour lysis syndrome. We review the limited literature discussing peritoneal lymphomatosis and discuss the importance of facilitating rapid and efficacious treatment.

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