De novo hepatocellular carcinoma 18 years after liver and small bowel transplantation in a one-year-old pediatric patient.

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Citation: Pediatric Transplantation. 25(2):e13820, 2021 03.PMID: 32844551Institution: MedStar Washington Hospital CenterDepartment: Neonatology and Pediatrics | Surgery/TransplantationForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: *Carcinoma, Hepatocellular/et [Etiology] | *Intestine, Small/tr [Transplantation] | *Liver Neoplasms/et [Etiology] | *Liver Transplantation | *Postoperative Complications | *Short Bowel Syndrome/su [Surgery] | Carcinoma, Hepatocellular/di [Diagnosis] | Fatal Outcome | Humans | Infant | Liver Neoplasms/di [Diagnosis] | Male | Postoperative Complications/di [Diagnosis] | Young AdultYear: 2021ISSN:
  • 1397-3142
Name of journal: Pediatric transplantationAbstract: De novo HCC following transplantation in a child is a rare occurrence. Even within the adult liver transplantation population, there are a limited number of published cases. In this report, we present a case of de novo HCC found in a child, post-multivisceral transplantation. A 19-year-old boy, at the age of one, received liver and small bowel transplantation due to short gut syndrome secondary to midgut volvulus and total parenteral nutrition-associated liver disease. Eighteen years later, he was found to have a large mass involving the right hepatic dome consistent with HCC. To the best of our knowledge, this is the second reported case after gut transplantation and the third case post-liver transplantation in the pediatric population. Copyright (c) 2020 Wiley Periodicals LLC.All authors: Bryan N, Fishbein T, Girlanda R, Hawksworth J, Kallakury B, Kaufman S, Khan K, Kroemer A, Matsumoto C, Yazigi N, Zandieh AOriginally published: Pediatric Transplantation. :e13820, 2020 Aug 25Fiscal year: FY2021Digital Object Identifier: ORCID: Date added to catalog: 2020-10-06
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Journal Article MedStar Authors Catalog Article 32844551 Available 32844551

De novo HCC following transplantation in a child is a rare occurrence. Even within the adult liver transplantation population, there are a limited number of published cases. In this report, we present a case of de novo HCC found in a child, post-multivisceral transplantation. A 19-year-old boy, at the age of one, received liver and small bowel transplantation due to short gut syndrome secondary to midgut volvulus and total parenteral nutrition-associated liver disease. Eighteen years later, he was found to have a large mass involving the right hepatic dome consistent with HCC. To the best of our knowledge, this is the second reported case after gut transplantation and the third case post-liver transplantation in the pediatric population. Copyright (c) 2020 Wiley Periodicals LLC.

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