Obstetric complications among US women with asthma.

MedStar author(s):
Citation: American Journal of Obstetrics & Gynecology. 208(2):127.e1-8, 2013 Feb.PMID: 23159695Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology, Maternal-Fetal MedicineForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, N.I.H., IntramuralSubject headings: *Asthma/co [Complications] | *Delivery, Obstetric/mt [Methods] | *Pregnancy Complications | *Pregnancy Outcome/ep [Epidemiology] | Adult | Cesarean Section/sn [Statistics & Numerical Data] | Cohort Studies | Diabetes, Gestational/ep [Epidemiology] | Diabetes, Gestational/et [Etiology] | Female | Humans | Odds Ratio | Placenta Diseases/ep [Epidemiology] | Placenta Diseases/et [Etiology] | Pre-Eclampsia/ep [Epidemiology] | Pre-Eclampsia/et [Etiology] | Pregnancy | Premature Birth/ep [Epidemiology] | Premature Birth/et [Etiology] | Retrospective Studies | United States/ep [Epidemiology]Year: 2013Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006ISSN:
  • 0002-9378
Name of journal: American journal of obstetrics and gynecologyAbstract: CONCLUSION: Maternal asthma increased risk for nearly all outcomes studied in a general obstetric population. Copyright 2013 Mosby, Inc. All rights reserved.OBJECTIVE: We sought to characterize complications of pregnancy, labor, and delivery associated with maternal asthma in a contemporary US cohort.RESULTS: Women with asthma had higher odds of preeclampsia (adjusted odds ratio [aOR], 1.14; 95% confidence interval [CI], 1.06-1.22), superimposed preeclampsia (aOR, 1.34; 95% CI, 1.15-1.56), gestational diabetes (aOR, 1.11; 95% CI, 1.03-1.19), placental abruption (aOR, 1.22; 95% CI, 1.09-1.36), and placenta previa (aOR, 1.30; 95% CI, 1.08-1.56). Asthmatic women had a higher odds of preterm birth overall (aOR, 1.17; 95% CI, 1.12-1.23) and of medically indicated preterm delivery (aOR, 1.14; 95% CI, 1.01-1.29). Asthmatics were less likely to have spontaneous labor (aOR, 0.87; 95% CI, 0.84-0.90) and vaginal delivery (aOR, 0.84; 95% CI, 0.80-0.87). Risks were higher for breech presentation (aOR, 1.13; 95% CI, 1.05-1.22), hemorrhage (aOR, 1.09; 95% CI, 1.03-1.16), pulmonary embolism (aOR, 1.71; 95% CI, 1.05-2.79), and maternal intensive care unit admission (aOR, 1.34; 95% CI, 1.04-1.72).STUDY DESIGN: We studied a retrospective cohort based on electronic medical record data from 223,512 singleton deliveries from 12 clinical centers across the United States from 2002 through 2008.All authors: Chen Z, Laughon SK, Leishear K, Mannisto TI, Mendola P, Reddy UM, Zhang JFiscal year: Digital Object Identifier: Date added to catalog: 2013-09-17
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article Available 23159695

Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006

CONCLUSION: Maternal asthma increased risk for nearly all outcomes studied in a general obstetric population. Copyright 2013 Mosby, Inc. All rights reserved.

OBJECTIVE: We sought to characterize complications of pregnancy, labor, and delivery associated with maternal asthma in a contemporary US cohort.

RESULTS: Women with asthma had higher odds of preeclampsia (adjusted odds ratio [aOR], 1.14; 95% confidence interval [CI], 1.06-1.22), superimposed preeclampsia (aOR, 1.34; 95% CI, 1.15-1.56), gestational diabetes (aOR, 1.11; 95% CI, 1.03-1.19), placental abruption (aOR, 1.22; 95% CI, 1.09-1.36), and placenta previa (aOR, 1.30; 95% CI, 1.08-1.56). Asthmatic women had a higher odds of preterm birth overall (aOR, 1.17; 95% CI, 1.12-1.23) and of medically indicated preterm delivery (aOR, 1.14; 95% CI, 1.01-1.29). Asthmatics were less likely to have spontaneous labor (aOR, 0.87; 95% CI, 0.84-0.90) and vaginal delivery (aOR, 0.84; 95% CI, 0.80-0.87). Risks were higher for breech presentation (aOR, 1.13; 95% CI, 1.05-1.22), hemorrhage (aOR, 1.09; 95% CI, 1.03-1.16), pulmonary embolism (aOR, 1.71; 95% CI, 1.05-2.79), and maternal intensive care unit admission (aOR, 1.34; 95% CI, 1.04-1.72).

STUDY DESIGN: We studied a retrospective cohort based on electronic medical record data from 223,512 singleton deliveries from 12 clinical centers across the United States from 2002 through 2008.

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