MARC details
000 -LEADER |
fixed length control field |
03029nam a22005177a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210217s20212021 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0012-2823 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
000512682 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1159/000512682 [doi] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33477149 |
245 ## - TITLE STATEMENT |
Title |
Association of Serum Triglyceride Levels with Severity in Acute Pancreatitis: Results from an International, Multicenter Cohort Study. |
251 ## - Source |
Source |
Digestion. 102(5):809-813, 2021. |
252 ## - Abbreviated Source |
Abbreviated source |
Digestion. 102(5):809-813, 2021. |
252 ## - Abbreviated Source |
Former abbreviated source |
Digestion. :1-5, 2021 Jan 21 |
253 ## - Journal Name |
Journal name |
Digestion |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2021 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2021-02-17 |
268 ## - Previous citation |
-- |
Digestion. :1-5, 2021 Jan 21 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Hypertriglyceridemia (HTG) is considered within the top 5 etiologies in acute pancreatitis (AP), but the association of serum triglyceride (TG) levels with the clinical course of AP remains controversial. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: This large multicenter study confirms that elevated TG levels are associated with severe disease regardless of AP etiology. Copyright (c) 2021 S. Karger AG, Basel. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Patients were enrolled prospectively through APPRENTICE. High TG levels were defined based on the Endocrine Society Clinical Practice Guidelines. HTG was categorized as mild (serum TG levels 150-199 mg/dL), moderate (200-999 mg/dL), severe (1,000-1,999 mg/dL), and very severe (>=2,000 mg/dL). Severity of AP was based on the revised Atlanta classification criteria. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: This study aims to examine the effect of TG levels on severity of AP. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Early TG levels were measured in 764 subjects and found elevated in 342 (120 with mild; 176, moderate; and 46, severe/very severe HTG). Patients with increased TG levels were younger (age >=60, 16.7 vs. 30.3%), more likely to be male (66.1 vs. 51.2%), with more frequent alcohol use (62.8 vs. 50.7%), and diabetes mellitus (30.2 vs. 12.3%; all p <= 0.005). Severe AP (24.9 vs. 10.0%), ICU admission (32.5 vs. 19.7%), and mortality (5.3 vs. 1.7%; all p <= 0.005) were more frequently seen in patients with elevated TG levels. Based on multivariable analysis, elevated TG levels were independently associated with severe AP (p < 0.05). |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Pancreatitis |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Acute Disease |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cohort Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Retrospective Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Risk Factors |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Severity of Illness Index |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Triglycerides |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/General Internal Medicine |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
News |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Pothoulakis, Ioannis |
790 ## - Authors |
All authors |
Archibugi L, Capurso G, Lahooti A, Papachristou GI, Paragomi P, Pothoulakis I, Tuft M |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1159/000512682">https://dx.doi.org/10.1159/000512682</a> |
Public note |
https://dx.doi.org/10.1159/000512682 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |