Association of Serum Triglyceride Levels with Severity in Acute Pancreatitis: Results from an International, Multicenter Cohort Study. (Record no. 6042)

MARC details
000 -LEADER
fixed length control field 03029nam a22005177a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210217s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0012-2823
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 000512682 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1159/000512682 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33477149
245 ## - TITLE STATEMENT
Title Association of Serum Triglyceride Levels with Severity in Acute Pancreatitis: Results from an International, Multicenter Cohort Study.
251 ## - Source
Source Digestion. 102(5):809-813, 2021.
252 ## - Abbreviated Source
Abbreviated source Digestion. 102(5):809-813, 2021.
252 ## - Abbreviated Source
Former abbreviated source Digestion. :1-5, 2021 Jan 21
253 ## - Journal Name
Journal name Digestion
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2021-02-17
268 ## - Previous citation
-- Digestion. :1-5, 2021 Jan 21
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Hypertriglyceridemia (HTG) is considered within the top 5 etiologies in acute pancreatitis (AP), but the association of serum triglyceride (TG) levels with the clinical course of AP remains controversial.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: This large multicenter study confirms that elevated TG levels are associated with severe disease regardless of AP etiology. Copyright (c) 2021 S. Karger AG, Basel.
520 ## - SUMMARY, ETC.
Abstract METHODS: Patients were enrolled prospectively through APPRENTICE. High TG levels were defined based on the Endocrine Society Clinical Practice Guidelines. HTG was categorized as mild (serum TG levels 150-199 mg/dL), moderate (200-999 mg/dL), severe (1,000-1,999 mg/dL), and very severe (>=2,000 mg/dL). Severity of AP was based on the revised Atlanta classification criteria.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVES: This study aims to examine the effect of TG levels on severity of AP.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Early TG levels were measured in 764 subjects and found elevated in 342 (120 with mild; 176, moderate; and 46, severe/very severe HTG). Patients with increased TG levels were younger (age >=60, 16.7 vs. 30.3%), more likely to be male (66.1 vs. 51.2%), with more frequent alcohol use (62.8 vs. 50.7%), and diabetes mellitus (30.2 vs. 12.3%; all p <= 0.005). Severe AP (24.9 vs. 10.0%), ICU admission (32.5 vs. 19.7%), and mortality (5.3 vs. 1.7%; all p <= 0.005) were more frequently seen in patients with elevated TG levels. Based on multivariable analysis, elevated TG levels were independently associated with severe AP (p < 0.05).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Pancreatitis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Acute Disease
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cohort Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Severity of Illness Index
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Triglycerides
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Medicine/General Internal Medicine
657 ## - INDEX TERM--FUNCTION
Medline publication type News
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Pothoulakis, Ioannis
790 ## - Authors
All authors Archibugi L, Capurso G, Lahooti A, Papachristou GI, Paragomi P, Pothoulakis I, Tuft M
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1159/000512682">https://dx.doi.org/10.1159/000512682</a>
Public note https://dx.doi.org/10.1159/000512682
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 02/17/2021   33477149 33477149 02/17/2021 02/17/2021 Journal Article

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