Increased body mass index predicts prolonged survival in patients with head and neck squamous cell carcinoma.
Increased body mass index predicts prolonged survival in patients with head and neck squamous cell carcinoma.
- 2022
Available online from MWHC library: 1996 - present
BACKGROUND: Higher body mass index (BMI) may have a protective effect on survival in patients with head and neck cancer. The aim of this study was to determine the effect of BMI on overall survival (OS) in veterans with head and neck squamous cell carcinoma (HNSCC). CONCLUSIONS: Higher BMI at diagnosis may have a protective effect on OS in veterans with HNSCC. Copyright ♭ 2021 Wiley Periodicals LLC. METHODS: A cohort of 702 patients diagnosed with HNSCC between 1995 and 2019 were identified at the Washington DC Veterans Affairs Medical Center, and 342 patients were included for analysis. Records were queried for clinical-demographic data, BMI, and outcomes. RESULTS: HNSCC patients categorized as overweight or obese at time of diagnosis had a lower 3-year risk of death (p = 0.033) and improved OS (p < 0.001) compared to patients who were underweight or normal weight. The majority of locoregional recurrences occurred in patients with low or normal pretreatment BMI.
English
1043-3074
10.1002/hed.26922 [doi]
*Head and Neck Neoplasms
*Neoplasm Recurrence, Local
Body Mass Index
Head and Neck Neoplasms/th [Therapy]
Humans
Obesity/co [Complications]
Obesity/ep [Epidemiology]
Prognosis
Squamous Cell Carcinoma of Head and Neck
MedStar Georgetown University Hospital/MedStar Washington Hospital Center
Otolaryngology Residency
Journal Article
Available online from MWHC library: 1996 - present
BACKGROUND: Higher body mass index (BMI) may have a protective effect on survival in patients with head and neck cancer. The aim of this study was to determine the effect of BMI on overall survival (OS) in veterans with head and neck squamous cell carcinoma (HNSCC). CONCLUSIONS: Higher BMI at diagnosis may have a protective effect on OS in veterans with HNSCC. Copyright ♭ 2021 Wiley Periodicals LLC. METHODS: A cohort of 702 patients diagnosed with HNSCC between 1995 and 2019 were identified at the Washington DC Veterans Affairs Medical Center, and 342 patients were included for analysis. Records were queried for clinical-demographic data, BMI, and outcomes. RESULTS: HNSCC patients categorized as overweight or obese at time of diagnosis had a lower 3-year risk of death (p = 0.033) and improved OS (p < 0.001) compared to patients who were underweight or normal weight. The majority of locoregional recurrences occurred in patients with low or normal pretreatment BMI.
English
1043-3074
10.1002/hed.26922 [doi]
*Head and Neck Neoplasms
*Neoplasm Recurrence, Local
Body Mass Index
Head and Neck Neoplasms/th [Therapy]
Humans
Obesity/co [Complications]
Obesity/ep [Epidemiology]
Prognosis
Squamous Cell Carcinoma of Head and Neck
MedStar Georgetown University Hospital/MedStar Washington Hospital Center
Otolaryngology Residency
Journal Article