High-grade pleomorphic rhabdomyosarcoma in a 60-year-old male: a case report and review of the literature.
High-grade pleomorphic rhabdomyosarcoma in a 60-year-old male: a case report and review of the literature.
- 2020
Rhabdomyosarcoma is an aggressivemalignant soft-tissue sarcoma that develop from undifferentiated mesenchymal cells. Less than 1% of all adult solid malignant cancers are sarcomas, and RMSs represent less than 2-5% of adult sarcomas. RMS is divided into three main subtypes: Embryonal, alveolar and pleomorphic RMS (PRMS). Most common subtype in adults is PRMS. Most common primary sites are extremities, trunk wall, and genitourinary organs. Metastasis are often found at diagnosis. 5-year overall survival rates were reported in the Surveillance, Epidemiology, and End Results database (SEER) to be 63% for pediatric patients and 27% for adults. Given the rarity of theadultPRMS, variation in its clinical presentation, characteristics of the tumor itself and the prognosis; there are very limited data available to guide the management of adults withPRMS.Herein we present a case report of pleomorphic rhabdomyosarcoma of the right thigh in a 60-year-old male who achieved along-termsurvival (30 months) which was accomplished by multimodality treatment including surgery, radiotherapy, and chemotherapy.. Copyright (c) 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center.
English
2000-9666
10.1080/20009666.2020.1766820 [doi] 1766820 [pii] PMC7426990 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Good Samaritan Hospital
MedStar Union Memorial Hospital
Internal Medicine
Medicine
MedStar Health Baltimore Residents
Case Reports
Rhabdomyosarcoma is an aggressivemalignant soft-tissue sarcoma that develop from undifferentiated mesenchymal cells. Less than 1% of all adult solid malignant cancers are sarcomas, and RMSs represent less than 2-5% of adult sarcomas. RMS is divided into three main subtypes: Embryonal, alveolar and pleomorphic RMS (PRMS). Most common subtype in adults is PRMS. Most common primary sites are extremities, trunk wall, and genitourinary organs. Metastasis are often found at diagnosis. 5-year overall survival rates were reported in the Surveillance, Epidemiology, and End Results database (SEER) to be 63% for pediatric patients and 27% for adults. Given the rarity of theadultPRMS, variation in its clinical presentation, characteristics of the tumor itself and the prognosis; there are very limited data available to guide the management of adults withPRMS.Herein we present a case report of pleomorphic rhabdomyosarcoma of the right thigh in a 60-year-old male who achieved along-termsurvival (30 months) which was accomplished by multimodality treatment including surgery, radiotherapy, and chemotherapy.. Copyright (c) 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center.
English
2000-9666
10.1080/20009666.2020.1766820 [doi] 1766820 [pii] PMC7426990 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Good Samaritan Hospital
MedStar Union Memorial Hospital
Internal Medicine
Medicine
MedStar Health Baltimore Residents
Case Reports