Normal view MARC view ISBD view

High-grade pleomorphic rhabdomyosarcoma in a 60-year-old male: a case report and review of the literature.

MedStar author(s):

Citation: Journal of Community Hospital Internal Medicine Perspectives. 10(3):287-289, 2020 Jun 14.PMID: 32850081Institution: MedStar Good Samaritan Hospital | MedStar Union Memorial HospitalDepartment: Internal Medicine | Medicine | MedStar Health Baltimore ResidentsForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2020 ISSN:

2000-9666

Name of journal: Journal of community hospital internal medicine perspectivesAbstract: Rhabdomyosarcoma is an aggressivemalignant soft-tissue sarcoma that develop from undifferentiated mesenchymal cells. Less than 1% of all adult solid malignant cancers are sarcomas, and RMSs represent less than 2-5% of adult sarcomas. RMS is divided into three main subtypes: Embryonal, alveolar and pleomorphic RMS (PRMS). Most common subtype in adults is PRMS. Most common primary sites are extremities, trunk wall, and genitourinary organs. Metastasis are often found at diagnosis. 5-year overall survival rates were reported in the Surveillance, Epidemiology, and End Results database (SEER) to be 63% for pediatric patients and 27% for adults. Given the rarity of theadultPRMS, variation in its clinical presentation, characteristics of the tumor itself and the prognosis; there are very limited data available to guide the management of adults withPRMS.Herein we present a case report of pleomorphic rhabdomyosarcoma of the right thigh in a 60-year-old male who achieved along-termsurvival (30 months) which was accomplished by multimodality treatment including surgery, radiotherapy, and chemotherapy.. Copyright (c) 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center.All authors: Kanwal A, Mustafa S, Taza F, Zulty MFiscal year: FY2021Digital Object Identifier:

https://dx.doi.org/10.1080/20009666.2020.1766820

ORCID:

Date added to catalog: 2020-10-06

Holdings ( 1 )
Title notes ( 2 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	32850081	Available		32850081

Rhabdomyosarcoma is an aggressivemalignant soft-tissue sarcoma that develop from undifferentiated mesenchymal cells. Less than 1% of all adult solid malignant cancers are sarcomas, and RMSs represent less than 2-5% of adult sarcomas. RMS is divided into three main subtypes: Embryonal, alveolar and pleomorphic RMS (PRMS). Most common subtype in adults is PRMS. Most common primary sites are extremities, trunk wall, and genitourinary organs. Metastasis are often found at diagnosis. 5-year overall survival rates were reported in the Surveillance, Epidemiology, and End Results database (SEER) to be 63% for pediatric patients and 27% for adults. Given the rarity of theadultPRMS, variation in its clinical presentation, characteristics of the tumor itself and the prognosis; there are very limited data available to guide the management of adults withPRMS.Herein we present a case report of pleomorphic rhabdomyosarcoma of the right thigh in a 60-year-old male who achieved along-termsurvival (30 months) which was accomplished by multimodality treatment including surgery, radiotherapy, and chemotherapy.. Copyright (c) 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center.

English