Topical sirolimus for treatment of a venolymphatic malformation in an adolescent girl.
Topical sirolimus for treatment of a venolymphatic malformation in an adolescent girl.
- 2018
Copyright (c) 2018 Wiley Periodicals, Inc. Sirolimus has emerged as a promising treatment for complex congenital vascular malformations but is limited because of systemic side effects. Topically compounded formulations, which have been found to be successful in the treatment of several other conditions, are a preferred drug delivery system to provide local therapy. We report a case of a venolymphatic malformation in an adolescent girl treated with topical 1% sirolimus cream leading to improvement in appearance and associated symptoms.
English
0736-8046
10.1111/pde.13622 [doi]
*Immunosuppressive Agents/ad [Administration & Dosage]
*Sirolimus/ad [Administration & Dosage]
*Vascular Malformations/dt [Drug Therapy]
Administration, Topical
Adolescent
Female
Humans
Treatment Outcome
MedStar Washington Hospital Center
Dermatology
Journal Article
Copyright (c) 2018 Wiley Periodicals, Inc. Sirolimus has emerged as a promising treatment for complex congenital vascular malformations but is limited because of systemic side effects. Topically compounded formulations, which have been found to be successful in the treatment of several other conditions, are a preferred drug delivery system to provide local therapy. We report a case of a venolymphatic malformation in an adolescent girl treated with topical 1% sirolimus cream leading to improvement in appearance and associated symptoms.
English
0736-8046
10.1111/pde.13622 [doi]
*Immunosuppressive Agents/ad [Administration & Dosage]
*Sirolimus/ad [Administration & Dosage]
*Vascular Malformations/dt [Drug Therapy]
Administration, Topical
Adolescent
Female
Humans
Treatment Outcome
MedStar Washington Hospital Center
Dermatology
Journal Article