Evidence Regarding Pharmacogenetics in Pain Management and Cancer.

Evidence Regarding Pharmacogenetics in Pain Management and Cancer. - 2023

Patients experience interindividual variation in response to analgesics, which may be partially explained by genetics. This commentary discusses a recently published trial on COMT genotype and opioid dose requirements and describes the potential role for COMT and other genes (eg, CYP2D6) on opioid therapy and the current evidence for germline pharmacogenetics and resources for opioid pharmacogenetics. Copyright © The Author(s) 2023. Published by Oxford University Press.


English

1083-7159

10.1093/oncolo/oyac277 [doi] 7010651 [pii]


IN PROCESS -- NOT YET INDEXED


MedStar Health
Pharmacogenomics


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