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Durable Polymer Drug Eluting Stent-Induced Kounis Syndrome and Eosinophilia Requiring Long-term Immunosuppression. - 2022

There are no reports of systemic eosinophilic reactions to durable polymer coated drug eluting stents (DP-DES) and a consensus statement indicates that these devices should be considered in nickel allergy. We present a case of in-stent thrombosis, eosinophilia, and rash consistent with allergic myocardial infarction, a presentation of Kounis syndrome, in the context of metal allergy to DP-DES requiring long-term immunosuppression. Copyright (c) 2021. Published by Elsevier Inc.


English

ISSN: 0828-282X

Standard No.: 10.1016/j.cjca.2021.12.001 [doi] S0828-282X(21)00924-7 [pii]

Subjects--Topical Terms:
*Drug-Eluting Stents/ae [Adverse Effects]
*Eosinophilia
*Kounis Syndrome
*Nickel
*Percutaneous Coronary Intervention
*Prednisone/ad [Administration & Dosage]
Aged, 80 and over
Diagnosis, Differential
Eosinophilia/di [Diagnosis]
Eosinophilia/et [Etiology]
Humans
Immunosuppressive Agents/ad [Administration & Dosage]
Kounis Syndrome/di [Diagnosis]
Kounis Syndrome/dt [Drug Therapy]
Kounis Syndrome/et [Etiology]
Kounis Syndrome/pp [Physiopathology]
Male
Metals, Heavy/ae [Adverse Effects]
Metals, Heavy/an [Analysis]
Nickel/ae [Adverse Effects]
Nickel/an [Analysis]
Non-ST Elevated Myocardial Infarction/su [Surgery]
Percutaneous Coronary Intervention/ae [Adverse Effects]
Percutaneous Coronary Intervention/is [Instrumentation]
Percutaneous Coronary Intervention/mt [Methods]
Skin Tests/mt [Methods]

Subjects--Geographic Terms:
MedStar Heart & Vascular Institute

Index Terms--Function:
Case Reports