MARC details
| 000 -LEADER |
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| fixed length control field |
03624nam a22005177a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
180706s20182018 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1083-3188 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.jpag.2018.06.006 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S1083-3188(18)30247-X [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
29940314 |
| 245 ## - TITLE STATEMENT |
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| Title |
Non-Cytotoxic Related Primary Ovarian Insufficiency in Adolescents: Multicenter Case Series and Review. |
| 251 ## - Source |
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| Source |
Journal of Pediatric & Adolescent Gynecology. 31(6):597-604, 2018 Dec. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Pediatr Adolesc Gynecol. 31(6):597-604, 2018 Dec. |
| 253 ## - Journal Name |
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| Journal name |
Journal of pediatric and adolescent gynecology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2018 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2019 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2018-07-06 |
| 269 ## - Original dates |
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| Original fiscal year |
FY2018 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online through MWHC library: 2002 - present |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Non-cytotoxic POI in adolescents is an uncommon condition with only 64 cases in 6 institutions over 7 years. These patients may not undergo complete etiological workup. Aside from 45X, the most common etiologies are X-chromosome abnormalities or galactosemia. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright (c) 2018 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
DESIGN: Case series of patients with POI. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
INTERVENTIONS: Review and data extraction of records identified with ICD-9 and ICD-10 codes. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MAIN OUTCOME MEASURE(S): Data were analyzed for signs and symptoms, workup, and treatments. Complete work-up was based on ACOG guidelines. Characteristics of patients with POI presenting with delayed puberty/primary amenorrhea vs secondary amenorrhea were compared. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: 135 records were identified. Those who had received cytotoxic therapy (n=52), 46XY gonadal dysgenesis (n=7),or on review did not have POI (n=19) were excluded. Of 57 remaining cases, 16 were 45X, 2 had galactosemia and 4 had X-chromosome abnormalities. Most did not undergo full etiologic evaluation. Girls diagnosed following primary amenorrhea/delayed puberty were less symptomatic and more likely to receive an estrogen patch than those diagnosed following secondary amenorrhea. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
SETTING: Six tertiary care institutions ParticipantsPatients presenting from 2007-2014 aged 13-21 years diagnosed with non-cytotoxic POI, exclusions gonadotoxic therapy, 46XY gonadal dysgenesis, lack of evidence of hypergonadotropic hypogonadism on chart review. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
STUDY OBJECTIVE: Primary ovarian insufficiency (POI) in adolescents not due to cytotoxic therapy has not been well studied. Causes of POI have been described in adults, but adolescents may represent a unique subset necessitating a targeted approach to diagnosis, work-up and treatment. We sought to better characterize adolescent POI through a descriptive multicenter study. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Primary Ovarian Insufficiency/et [Etiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Adolescent |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Amenorrhea/et [Etiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Gonadal Dysgenesis/co [Complications] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Puberty, Delayed/et [Etiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Young Adult |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Obstetrics and Gynecology/Pediatric and Adolescent |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Gomez-Lobo, Veronica |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Patel, Vrunda |
| 790 ## - Authors |
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| All authors |
Davis Kankanamge C, Gomez-Lobo V, Hakim JC, Kanner L, Patel V, Podany E, Yu V |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.jpag.2018.06.006">https://dx.doi.org/10.1016/j.jpag.2018.06.006</a> |
| Public note |
https://dx.doi.org/10.1016/j.jpag.2018.06.006 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
