Predictors of 130912 in pain and physical functioning among post-menopausal women with recurrent pain conditions in the women's health initiative observational cohort.
Citation: Journal of Pain. 13(1):64-72, 2012 Jan.PMID: 22208802Institution: MedStar Washington Hospital CenterDepartment: Medicine/RheumatologyForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S.Subject headings: *Health Status | *Motor Activity/ph [Physiology] | *Pain/ep [Epidemiology] | *Pain/pp [Physiopathology] | *Women's Health | Aged | Body Mass Index | Cohort Studies | Depression | Female | Humans | Logistic Models | Longitudinal Studies | Middle Aged | Observation | Pain/dt [Drug Therapy] | Pain/px [Psychology] | Postmenopause | Predictive Value of Tests | Quality of Life | Randomized Controlled Trials as TopicYear: 2012Local holdings: Available online from MWHC library: 2000 - 2008ISSN:- 1526-5900
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 22208802 | Available | 22208802 |
Available online from MWHC library: 2000 - 2008
Pain complaints are commonly reported symptoms among postmenopausal women and can have significant effects on health-related quality of life. We sought to identify medical and psychosocial factors that predict 130912s in pain and overall physical functioning over a 3-year period among postmenopausal women with recurrent pain conditions. We examined data from postmenopausal women age 50 to 79 with recurrent pain conditions (low back pain, neck pain, headache or migraines, or joint pain or stiffness) over a 3-year period using the Women's Health Initiative Observational Study Cohort (N = 67,963). Multinomial logistic regression models controlling for demographic and clinical characteristics were used to identify baseline predictors of 130912 in the SF-36 subscales for pain and physical functioning between baseline and 3-year follow-up. Body mass index (BMI) was associated with worsening of pain (OR [95% CI] 1.54 [1.45-1.63] for BMI >=30) and physical functioning (1.83 [1.71-1.95] for BMI >=30). A higher reported number of nonpain symptoms, higher medical comorbidity, and a positive screen for depression (1.13 [1.05-1.22] for worsened pain) were also associated with worsening of pain and physical functioning. Baseline prescription opioid use was also associated with lack of improvement in pain (OR .42, 95% CI .36-.49) and with worsened physical functioning (1.25 [1.04-1.51]). PERSPECTIVE: This study presents prospective data on 130912 in pain and physical functioning in postmenopausal women over a 3-year period. Our results suggest depression, nonpain physical symptoms, obesity, and possibly opioid treatment are associated with worse long-term pain outcomes in this population. Copyright 2012 American Pain Society. Published by Elsevier Inc. All rights reserved.
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